… of atovaquone-proguanil–resistant Plasmodium falciparum malaria acquired by a nonimmune
traveler to … Treatment failure was confirmed by genetic fingerprinting and sequencing. The …

… We describe the first reported case in North America of genetically confirmed atovaquone/proguanil-resistant
P. falciparum malaria. Polymerase chain … traveler to east Africa. Clin …

… Continuous monitoring of atovaquone-proguanil resistant P. … new antimalarial drug,
especially in non-immune travelers. … (Nigeria and Senegal) and East Africa (Malawi) where AP is …

… multiple mutations in the P falciparum dihydrofolate reductase (pfdhfr) gene. These mutations
… We were not able to perform in vitro susceptibility testing or confirm adequate blood levels …

… Atovaquone/proguanil-resistant parasite was detectable only in the post-… traveler to East
Africa. … treatment of Plasmodium falciparum malaria acquired by a non-immune North American …

… Plasmodium falciparum malaria acquired by a non-immune … We report the first genetically
confirmed case of atovaquone-… the first known case of atovaquone/proguanil-resistant P. …

… malaria in non-immune travelers, treated with either AP or AL. … from Africa, six from West
Africa, and one from East Africa (AP … falciparum malaria acquired in Africa. Thus, the WHO …

… Since 2002, fewer than 20 cases of genetically confirmed … of Plasmodium falciparum
malaria acquired by a non-immune … malaria acquired by a nonimmune traveller to east Africa. …

… mutations of the Plasmodium falciparum cytochrome b gene (… of malaria had been acquired
in West Africa, 1 in East Africa, … travelers returning from regions where falciparum malaria is …

… antimalarial drug, mostly used for treatment and chemoprophylaxis of falciparum malaria for
international travelers (… sequenced to confirm PCR-RFLP results using an ABI Prism 3500xL …